Bringing science and development together through news and analysis

  • Cholera and typhoid vaccines on trial in India


This year, 60,000 slum-dwellers in Kolkata, India, will take part in a trial testing the safety and effectiveness of an oral cholera vaccine.

Last November, the same population was injected with a potential typhoid vaccine, reports Paroma Basu in this article in Nature.

Besides their obvious benefits, the trials have highlighted the difficulties in carrying out large-scale clinical research in developing countries, says Basu.

As well as facing various bureaucratic hurdles, the researchers found it especially hard to gain the confidence of potential participants.

They succeeded in building a degree of trust by employing 250 citizens as health workers and sample collectors. The researchers believe this is the reason they managed to obtain informed consent from so many people. 

Link to full article in Nature

We encourage you to republish this article online and in print, it’s free under our creative commons attribution license, but please follow some simple guidelines:
  1. You have to credit our authors.
  2. You have to credit SciDev.Net — where possible include our logo with a link back to the original article.
  3. You can simply run the first few lines of the article and then add: “Read the full article on SciDev.Net” containing a link back to the original article.
  4. If you want to also take images published in this story you will need to confirm with the original source if you're licensed to use them.
  5. The easiest way to get the article on your site is to embed the code below.
For more information view our media page and republishing guidelines.