Written for lay people who are considering becoming trial volunteers, this brief guide outlines the purpose and nature of HIV vaccine trials, and stresses the varying benefits of a vaccine.
These range from preventing infection in most or just some people (a preventive vaccine), to delaying or preventing the onset of illness or AIDS in people who are already infected with HIV (a therapeutic vaccine). Even a vaccine that is only partially effective could decrease the number of people who get infected.

It also indicates the need for advice on issues such as insurance and travel, as routine blood tests for the presence of antibodies to HIV will not distinguish between whether a person has received a vaccine or is infected with HIV (although other tests can be used for this).

[The guide is also available in Spanish.]


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