In this commentary article Anthony Fauci, Director of the US National Institutes of Health Division of AIDS, pays tribute to the extraordinary achievements in HIV/AIDS research over the past 20 years.

Scientific advances in understanding the biology of HIV infection and disease have paved the way for new treatments and raise the prospects for the creation of an effective vaccine. However, Fauci notes that understanding the correlates of immune protection and their potential role in vaccine development remains one of the greatest challenges in HIV and AIDS research.

Although the article assumes a working knowledge of biology, it provides an unusual historical perspective on the pace and range of scientific advances in HIV/AIDS science.


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