This journal article describes the first climate-based model used to predict outbreaks of dengue fever. Researchers from the University of Miami and the University of Costa Rica used climate data and vegetation indices from Costa Rica to predict disease outbreaks with 83 per cent accuracy.

Globally, there are up to 100 million cases of dengue fever, and its more dangerous form, dengue haemorrhagic fever, every year. The spread of dengue fever is set to rise as the world's climate changes. The importance of this model is that it could be used as the basis for an early warning system to prevent the spread of the disease by warning populations that are at risk.

The indices used in the model include variables such as El Niño Southern Oscillations and sea surface temperature, which affect populations of the Aedes aegypti mosquito that spreads the infection.