This safety guide, published by the International Atomic Energy Agency (IAEA), is designed to help countries prepare plans to improve their capacity to respond to nuclear or radiological emergencies whether as a result of an accident or malicious use of nuclear material. The guide can also be used to meet IAEA's safety requirements.

It outlines generic and operational criteria, according to specific radiation doses, to help policymakers decide between different courses of action to protect the public, emergency workers and the environment. It includes guidelines for assessing food and water contamination, and subsequent remediation measures, as well as on how to set safety perimeters around an incident depending on initial observations at the scene. The guide also outlines lessons learned from past experiences.