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The largest planned AIDS vaccine trial to date, due to take place in Thailand, is to be delayed by at least a year.

Production problems and setbacks in renovating health centres and clinics in preparation for the trial have caused the delay.

The trial — which aims to test a pair of vaccines developed by Aventis Pasteur and VaxGen in 16,000 Thai participants — is only the second efficacy trial for an AIDS vaccine. The Thai ministry of health says that, despite the delays, volunteer recruitment for the trial should start in September.

Reference: Science, 17 January 2003

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