Progress and doubt in disease gene search project
The US$100 million International HapMap Project aims to identify genes responsible for common diseases such as diabetes by examining ethnically distinct human populations from the United States, Nigeria, China and Japan.
In this article, Jennifer Couzin describes progress made at the midway point of the three-year project.
Initial results are encouraging, and early disagreements about methodologies have been resolved. But, as the search for genes is getting cheaper and easier, questions remain about the design and value of the project.