Bringing science and development together through news and analysis

  • Researchers profile malaria's proteins


Researchers have taken snapshots of the ever-changing protein profile of the malaria parasite Plasmodium falciparum. Their findings may help identify new drug targets for the disease, which kills 3,000 children a day, mainly in Africa.

Elizabeth Winzeler of the Scripps Research Institute in California and colleagues devised a new technique to record the activity of genes at different stages in the parasite's lifecycle. They then inferred the probable functions of unknown genes from the timing and activity of known ones.

There are about 5,300 genes in the malaria parasite's genome, but only a third of these encode proteins with known functions. The new research – published in this week's Science Express – gives clues to the function of a further 1,000 possible proteins.

Link to Nature Science Update news story

We encourage you to republish this article online and in print, it’s free under our creative commons attribution license, but please follow some simple guidelines:
  1. You have to credit our authors.
  2. You have to credit SciDev.Net — where possible include our logo with a link back to the original article.
  3. You can simply run the first few lines of the article and then add: “Read the full article on SciDev.Net” containing a link back to the original article.
  4. If you want to also take images published in this story you will need to confirm with the original source if you're licensed to use them.
  5. The easiest way to get the article on your site is to embed the code below.
For more information view our media page and republishing guidelines.