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South-East Asia & Pacific

Key Documents

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Displaying 1-5 of 5 key documents

Global Drylands: A UN system-wide response

Source: United Nations Environment Management Group | October 2011

This report outlines the first coherent strategy drawn up by the UN to address dryland management, taking into account environmental concerns and the well-being of dryland communities. It examines the relationship between drylands and climate change, food security and livelihoods, and highlights ways in which the UN is working to mainstream drylands into policymaking processes.

Climate change is already having an impact on crop yields and nutrition in areas that rely on rain-fed agriculture, according to the report, and these impacts will intensify by 2020 in parts of Sub-Saharan Africa, Asia and Latin America. The impacts of climate change may be most pronounced in Sub-Saharan Africa and South Asia, suggesting that those already vulnerable will be affected the most.

A key message is that the international community has an opportunity to address the underlying causes of dryland degradation. The report concludes that global cooperation must be intensified if the ten-year strategic plan of the UN Convention to Combat Desertification — whose aim is to tackle desertification and degradation — and the Millennium Development Goals are to be achieved.

Vital forest graphics

Source: UN Environment Programme

This report advocates for the conservation and sustainable management of world's forests by highlighting the ways in which these support ecological stability, economic development and human well-being.

The authors present case studies from the Amazon, Central America and South-East Asia to discuss issues such as livelihoods, biofuel and indigenous people. An overview of the legal mechanisms to protect forests is also given.

Expanding priorities — confronting chronic disease in countries with low income

Source: NEJM | January, 2007

Cardiovascular disease accounts for 30% of deaths worldwide and 10% of all years of healthy life lost to disease, and the figures are nearly as high in developing countries — 27 per cent and 9 per cent respectively. This compares with 10% of lives lost worldwide from HIV/AIDS, TB and malaria put together (12% in developing countries). So why have donors not invested as heavily into tackling non-communicable chronic diseases as they have with infectious ones? The authors of this article suggest several reasons: infectious diseases are in some ways easier to solve by a vaccine or drugs so it might seem sensible to use precious funding this way; Western donors may want to see epidemics contained quickly to avoid global spread; pictures of small African children dying of AIDS are more heartrending than a middle-aged man with hypertension, even if that man is supporting a large family; there is a myth that chronic diseases are more costly to prevent than infectious ones. This last issue is one that should be tackled strongly to spread awareness that low-cost methods can have an enormous effect on chronic diseases.

Therapeutic vaccination for chronic diseases: a new class of drugs in sight

Source: Nature Reviews | January, 2004

Vaccination for infectious diseases is a vital method of prophylaxis, and has transformed modern medicine. By contrast, research into vaccines against chronic diseases has been less successful, in part because of the increased complexity involved.

In this opinion piece, the authors outline the prospects for the development of chronic disease vaccines. These might not need to rely on the traditional method of inducing the body to produce antibodies, but rather on introducing monoclonal antibodies against specific proteins — this has so far worked well against Crohn's disease and rheumatoid arthritis.

The authors outline key hurdles in developing a successful therapeutic vaccine. Safety and efficacy are two obvious ones, but there is a third that is unique to vaccines for chronic diseases. Because these vaccines would block bodily chemicals — such as cytokines or hormones — it would not be acceptable for a vaccine to induce a life-long block (unlike a malaria vaccine, for example, where a lifelong block would be ideal).

These might be particularly useful in developing countries, say the authors. Because prophylaxis with vaccines is already a familiar concept, there should be no problem with patients' compliance, and judicious partnerships between public and private organisations could mean the vaccines are produced cheaply.

Intellectual property, Intellectual Property, Drug Regulation, and Building Product Innovation Capability in Biotechnology: The Case of Hepatitis B Vaccine in Korea

Source: Innovation Strategy Today | 2005

This paper analyses the development of South Korea's hepatitis B vaccine industry. In particular, it examines how intellectual property and drug and vaccine regulations affected the industry's development.

Growth of South Korea's hepatitis B vaccine industry was supported by joint ventures allowing the acquisition of foreign knowledge, the potential market for the vaccine and the availability of skilled manpower. Also vital to the process were improvements in South Korea's regulations, which brought them more into line with international standards. The authors show that South Korea's success has policy implications for other countries. To reach the higher stages of innovative development in the biomedical industry, they say, developing countries examine R&D in the public and private sectors, high manufacturing standards, national and international distribution systems, intellectual property systems and regulatory systems.

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