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Key Documents archive results 1-20 of 81 in Health and HIV/AIDS
African AIDS vaccine programme for a coordinated and collaborative vaccine development effort on the continent
This paper, written by an international team of researchers, documents the work of the African AIDS Vaccine Programme (AAVP). It highlights the programme's impacts, successes and challenges, and looks to where the AAVP is heading. The AAVP, supported by the WHO and UNAIDS, is a network of...
KEY DOCUMENT | EN
HIV drug policies and South markets: settling controversies
This paper proposes a model to provide better access to fairly priced antiretroviral (ARV) drugs for HIV-infected people in poor countries, while also safeguarding the interests of ARV manufacturers. The authors explain what governments and brand and generic companies are doing to increase the...
KEY DOCUMENT | Publication date: September 2008 | EN
Health system reform in China
This series of commentaries and research articles -- published by The Lancet, the Peking University Health Sciences Centre and the China Medical Board -- addresses China's major health challenges, strategies and future. It has been produced by a group of 63 scientists from 10 countries with Chinese...
KEY DOCUMENT | Publication date: October 2008 | EN
Lancet special issue on HIV/AIDS
This special issue is a large collection of opinion pieces, research and review articles, and news features that highlight the advances in knowledge and challenges to the treatment and prevention of HIV/AIDS, including articles on randomised trials of promising HIV drugs. It also includes a look...
KEY DOCUMENT | Publication date: August 2006 | EN
Food, nutrition and HIV: what next?
In June 2006, the UN emphasised the crucial role of food and nutrition in mitigating the effects of HIV/AIDS. This briefing paper explains how these issues are intertwined, and analyses why there has been little action in this area so far. When food is scarce, women tend to get the smallest...
KEY DOCUMENT | Publication date: August 2006 | EN
Scaling-up the HIV/AIDS response: from alignment and harmonisation to mutual accountability
This briefing paper highlights the challenges in harmonising efforts to provide universal HIV/AIDS care. The 'Three Ones' principles, set in place to make the global fight against HIV/AIDS more efficient, advocate one action framework to coordinate all partners, one national AIDS authority and one...
KEY DOCUMENT | Publication date: August 2006 | EN
AIDS epidemic update
This annual update gives an overview of the latest developments in the global HIV/AIDS epidemic and provides regional statistics on the diseases's spread. It shows that numbers of people living with HIV and the number of deaths from AIDS are growing. The report presents trends in HIV prevalence,...
KEY DOCUMENT | Publication date: December 2006 | EN
Malaria and HIV interactions and their implications for public health policy
For this report, malaria and HIV/AIDS specialists were consulted on interactions between the two diseases and how having both affects people's health. They said there is still much to learn about the biological and clinical effects that malaria and HIV/AIDS have on each other. But some conclusions...
KEY DOCUMENT | Publication date: June 2004 | EN
Malaria and HIV interactions and their implications for public health policy
For this report, malaria and HIV/AIDS specialists were consulted on interactions between the two diseases and how having both affects people's health. They said there is still much to learn about the biological and clinical effects that malaria and HIV/AIDS have on each other. But some conclusions...
KEY DOCUMENT | Publication date: June 2004 | EN
The Causes and consequences of HIV evolution
This review, although aimed primarily at a scientific audience, is a clearly written account of how HIV is believed to have evolved over the past 40 or so years since its spread to humans from apes. The authors argue for the importance of widespread monitoring of how HIV continues to change...
KEY DOCUMENT | Publication date: January 2004 | EN
South Africa — blazing a trail for African biotechnology
Based on data from 28 interviews among scientists, this commentary describes in clear terms how the health biotechnology industry is thriving in South Africa, nurtured by a confidence among scientists that arose originally with the development of mining and arms industry during the apartheid...
KEY DOCUMENT | Publication date: October 2004 | EN
Integrating HIV testing into immunological studies of non-HIV-related diseases
This Commentary describes the increasing ethical dilemmas now being faced by researchers in areas with high incidence of HIV/AIDS, as they investigate immune responses to non-HIV/AIDS diseases such as malaria. Studies of immune responses require an HIV test to check whether the research volunteer...
KEY DOCUMENT | Publication date: May 2005 | EN
Introducing new vaccines into developing countries: obstacles, opportunities and complexities
With over 350 vaccine candidates against 88 different pathogens, including HIV, now in development in academia and industry, this commentary, written for a broad audience, provides a broad overview of the current trends that will determine which candidates are most likely to reach the poor in...
KEY DOCUMENT | Publication date: April 2005 | EN
Antiretroviral treatment for HIV infection in developing countries: an attainable new paradigm
This commentary outlines in clear terms the justification for making antiretroviral drugs accessible on a large scale in developing countries, noting particularly that antiretroviral drugs are now affordable, available, and cost-effective when provided in conjunction with prevention measures, and...
KEY DOCUMENT | Publication date: December 2003 | EN
Social and environmental risk factors in the emergence of infectious diseases
This review puts the HIV/AIDS epidemic into perspective against other new and re-emerging diseases that have raged among human populations since the beginning of agriculture around 10,000 years ago, including SARS, bovine spongiform encephalopathy (BSE)/variant Creutzfeldt-Jakob disease (vCJD) and...
KEY DOCUMENT | Publication date: December 2004 | EN
The Development of Vaginal Microbicides for the Prevention of HIV Transmission
This short online review aimed at non-specialists summarises the current status of microbicides research, describing in clear and concise terms the different types of microbicides currently in clinical trials, how they act, and their potential shortcomings. It refers to the increasing political and...
KEY DOCUMENT | Publication date: May 2005 | EN
A strategic plan to accelerate development of an HIV vaccine
Launched to coincide with the 2004 International AIDS Conference in Bangkok, in this strategy document, the IAVI outlines plans to strengthen and expand the research and development pipeline of candidate HIV vaccines, and engage as partners those countries most affected by HIV/AIDS. Future...
KEY DOCUMENT | Publication date: August 2004 | EN
Will a pill a day prevent HIV?: Anticipating the results of the Tenofovir “PREP” trials
In response to controversy over a trial in Cambodia that was halted earlier this year, this document, written for a broad audience, addresses a range of issues regarding tests of the antiretroviral drug tenofovir in healthy uninfected individuals. The clinical trials, taking place in Africa, Asia...
KEY DOCUMENT | Publication date: March 2005 | EN
AIDS Vaccine Handbook. 2nd Edition: Global Perspectives
This collection of 43 essays is by people involved in HIV/AIDS research, community education, clinical trials and advocacy, and aims to both inform and encourage global action. Written in an easy-to-read style, it introduces many of the major scientific, policy, social, ethical and economic...
KEY DOCUMENT | Publication date: 2002 | EN
Is an Effective HIV Vaccine Feasible?
This news feature aimed at a broad scientific audience likens the perplexing task of trying to develop an HIV vaccine to Uflying without a compassV. HIV poses unique challenges, including its infinite variability and protective coating that masks it from antibodies, yet researchers have evidence...
KEY DOCUMENT | Publication date: July 2005 | EN
