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Key Documents archive results 1-20 of 27 in Health and Drug development
A survey of South–North health biotech collaboration
This article, written by scientists from Canada, China, Egypt and India, examines the spread of alliances in health biotechnology and the extent of collaboration in this sector between the South and the North. The authors surveyed 288 firms on South-North health biotech collaborations and use the...
KEY DOCUMENT | Publication date: March 2009 | EN
HIV drug policies and South markets: settling controversies
This paper proposes a model to provide better access to fairly priced antiretroviral (ARV) drugs for HIV-infected people in poor countries, while also safeguarding the interests of ARV manufacturers. The authors explain what governments and brand and generic companies are doing to increase the...
KEY DOCUMENT | Publication date: September 2008 | EN
Therapeutic vaccination for chronic diseases: a new class of drugs in sight
Vaccination for infectious diseases is a vital method of prophylaxis, and has transformed modern medicine. By contrast, research into vaccines against chronic diseases has been less successful, in part because of the increased complexity involved. In this opinion piece, the authors outline the...
KEY DOCUMENT | Publication date: January, 2004 | EN
Lancet chronic disease series
This series of five articles outlines new challenges and unsolved problems since the journal's last series in 2005. The first articlehttp://www.scidev.net/uploads/File/pdffiles/Lancet_series1.pdf ([189kB]) predicts the disease burden and economic losses that developing countries would face from...
KEY DOCUMENT | Publication date: December 2007 | EN
A strategic plan to accelerate development of an HIV vaccine
Launched to coincide with the 2004 International AIDS Conference in Bangkok, in this strategy document, the IAVI outlines plans to strengthen and expand the research and development pipeline of candidate HIV vaccines, and engage as partners those countries most affected by HIV/AIDS. Future...
KEY DOCUMENT | Publication date: August 2004 | EN
Will a pill a day prevent HIV?: Anticipating the results of the Tenofovir “PREP” trials
In response to controversy over a trial in Cambodia that was halted earlier this year, this document, written for a broad audience, addresses a range of issues regarding tests of the antiretroviral drug tenofovir in healthy uninfected individuals. The clinical trials, taking place in Africa, Asia...
KEY DOCUMENT | Publication date: March 2005 | EN
AIDS Vaccine Handbook. 2nd Edition: Global Perspectives
This collection of 43 essays is by people involved in HIV/AIDS research, community education, clinical trials and advocacy, and aims to both inform and encourage global action. Written in an easy-to-read style, it introduces many of the major scientific, policy, social, ethical and economic...
KEY DOCUMENT | Publication date: 2002 | EN
Is an Effective HIV Vaccine Feasible?
This news feature aimed at a broad scientific audience likens the perplexing task of trying to develop an HIV vaccine to Uflying without a compassV. HIV poses unique challenges, including its infinite variability and protective coating that masks it from antibodies, yet researchers have evidence...
KEY DOCUMENT | Publication date: July 2005 | EN
Demand for a preventive HIV vaccine: review of the literature
A policy working paper concerning the demand for an HIV vaccine usefully compares studies conducted globally and nationally, concerning both public and private sectors, in order to help inform future healthcare strategies and financial planning, and investment from industry in HIV vaccine research...
KEY DOCUMENT | Publication date: April 2005 | EN
Assessing the demand for an HIV vaccine
This policy brief highlights key issues in assessing the demand for an HIV vaccine, including what factors influence demand, such as efficacy and cost of vaccine candidates and acceptability among target populations, and differences between public and private sectors in their willingness to pay for...
KEY DOCUMENT | Publication date: April 2005 | EN
Investing in AIDS Vaccines: Estimated resources required to accelerate R&D
This is a useful policy paper that assesses the total level of spending needed for AIDS vaccine research and development in the near future and the gap between current and projected spending. It considers the main stumbling blocks in vaccine research and development that could be significantly...
KEY DOCUMENT | Publication date: June 2005 | EN
Promoting R&D in Preventive Health Technologies: Opportunities for the Indian pharmaceutical and biotechnology sector - policy research working paper
This report from a workshop on UPromoting R&D in Preventive Health Technologies,V held in India in December 2004 outlines the potential role that the biotechnology sector in India could have in HIV vaccine research and development. India, as other Uinnovative developing countriesV such as Brazil...
KEY DOCUMENT | Publication date: January 2005 | EN
Prospects for an AIDS vaccine
In this commentary article, HIV vaccine researcher Ron Desrosiers presents his view that the main reason we do not yet have a vaccine for HIV is due to unsolved scientific questions rather than a bottleneck in conducting clinical trials. Accordingly, he advocates a "renewed, coordinated and focused...
KEY DOCUMENT | Publication date: March 2004 | EN
Therapeutic AIDS Vaccines: Are They Feasible and is Their Development a Separate Endeavour from Preventive Vaccines?
In this article, Simon Noble, editor of IAVI Report, explores the prospects for a kind of HIV vaccine that aims to boost the immune response in people already infected with the virus, rather than what most vaccine researchers are working on, namely to protect against infection in the first place. ...
KEY DOCUMENT | Publication date: January 2004 | EN
HIV Medicine
This freely-available online medical textbook is written by expert clinicians in Europe and the United States in clear language that will have broad appeal to non-medical readers. Updated every year, it contains searchable information about the clinical manifestations of HIV/AIDS and its treatment,...
KEY DOCUMENT | Publication date: 2003 | EN
The Case for Microbicides: a Global Priority
This report - the result of a one-year literature review and consultation with experts - provides the case for developing microbicides, and contains a useful account of the recent history of the field. The report notes that although the previous five years had seen a dramatic increase in the number...
KEY DOCUMENT | Publication date: June 2001 | EN
Mobilization for Microbicides: the Decisive Decade
This short report summarises five different sets of priorities for action on microbicides: development, marketing, public health, consumer access and advocacy. These are the key points of reports from five Working Groups of experts, assembled by the Microbicide Initiative, an umbrella organisation...
KEY DOCUMENT | Publication date: February 2002 | EN
The Science of Microbicides: Accelerating Development
This 94-page document is an extensive state-of-the-art report by the Science Working Group of the Microbicide Initiative. With individual chapters authored by different scientific experts, it provides a scientific road map for the development of a safe effective vaginal microbicide against...
KEY DOCUMENT | Publication date: 2002 | EN
Microbicide to Prevent Heterosexual Transmission of HIV: Ten Years Down the Road
This review - which includes a moderate level of technical detail - covers both the progress of microbicides through laboratory and clinical testing, and the social science and market research that supports microbicides as an HIV prevention option. Particularly useful is the brief information...
KEY DOCUMENT | Publication date: January 2002 | EN
The Need for a Global HIV Vaccine Enterprise
In this article, leading vaccine researchers and advocates join forces to call for a global strategy for developing an effective HIV vaccine. The goal, they say, would be to unite teams of researchers in a series of coordinated global HIV vaccine centres, each with the critical mass, focus and...
KEY DOCUMENT | Publication date: June 2003 | EN
