This report outlines the first coherent strategy drawn up by the UN to address dryland management, taking into account environmental concerns and the well-being of dryland communities. It examines the relationship between drylands and climate change, food security and livelihoods, and highlights ways in which the UN is working to mainstream drylands into policymaking processes.

Climate change is already having an impact on crop yields and nutrition in areas that rely on rain-fed agriculture, according to the report, and these impacts will intensify by 2020 in parts of Sub-Saharan Africa, Asia and Latin America. The impacts of climate change may be most pronounced in Sub-Saharan Africa and South Asia, suggesting that those already vulnerable will be affected the most.

A key message is that the international community has an opportunity to address the underlying causes of dryland degradation. The report concludes that global cooperation must be intensified if the ten-year strategic plan of the UN Convention to Combat Desertification — whose aim is to tackle desertification and degradation — and the Millennium Development Goals are to be achieved.

This report from PLoS Medicine argues that nanotechnology has a role in the development of low-income countries. The authors survey 85 experts worldwide and rank the top ten nanotech applications most likely to benefit developing nations. They outline how these applications can help meet the Millennium Development Goals. The paper calls for an initiative to identify "grand challenges" in nanotechnology for global health, which since the publication of this paper are now underway.

Mohamed Hassan at the Academy of Sciences for the Developing World (TWAS) argues that the nanotechnology boom will not lead to a divide between developed and developing countries due to the transformation of 21st century global science. Hassan says Brazil, China and India are swiftly developing nanotech capabilities. Instead, he warns of a South-South divide as poorer nations struggle to catch up. To avoid this, Hassan recommends that developing nations create networks between universities and research centres to share nanotech expertise.

This report describes practices that small-scale farmers can use to adapt to climate change. The authors divide these practices into five categories: farm management and technology, farm financial management, diversification, government interventions in infrastructure, health and risk reduction. They conclude that farmers in developing countries are already using creative practices to manage climate challenges and that climate policies must strive to incorporate these.

The Millennium Development Goals (MDGs) practically define health efforts in the 21st century, but they virtually ignore non-communicable diseases such as mental health, say these authors. This is despite evidence that mental health disorders are among the most important cause of sickness and disability and even premature mortality. The authors argue that tackling mental health problems will be vital to achieving the MDGs, and three in particular — eradicating poverty, reducing child mortality, and improving maternal health.

Poverty and hunger are well-recognised risk factors for mental health, but mental health also makes it harder for people to escape the hunger trap. Mothers who are depressed during pregnancy and post natally, are more likely to have underweight babies; not only that, the illness means these mothers are more likely to stop breastfeeding and less likely to ensure their children are properly immunised than mothers without depression.

The authors advocate that strengthening basic health-care systems should be holistic. For example, developing countries need more and better-trained health workers but they should not only know how to deliver babies but also how to counsel new mothers. HIV/AIDS programmes, as another example, should ensure that individuals not only have good access to antiretrovirals but also to treatment for depression if they need it.

Schizophrenia is relatively rare — affecting 1% of the world's population — but is arguably one of the most severe mental illnesses. Diagnosing and treating it can be hard enough in developed countries; the challenges are magnified in developing nations with inadequate health systems; few trained staff; and pervasive social stigma. So how best to treat it? In this debate, three psychiatrists offer their different viewpoints.

Vikram Patel, at the London School of Hygiene and Tropical Medicine, says the shortage of mental health specialists means that the most effective way of spreading the expertise around might be for non-specialist health workers or community representatives to be trained to bear the brunt of providing first-line mental health services. Saeed Farooq, at Pakistan's Lady Reading Hospital, argues that the principles of the WHO's DOTS TB programme, in which patients are given an uninterrupted supply of medication taken under close supervision, could be used to treat schizophrenia. The rationale is that missing medication for schizophrenia, which can be common given the cognitive impairment associated with the illness, has serious consequences and can lead to much higher risks of relapse. R. Thara, director of the Schizophrenia Research Foundation, Chennai, India, advocates tackling stigma by offering proper treatment. In India at least, he says, the mystification of mental illness is intensified by a lack of awareness about schizophrenia and also by "magico-religious" beliefs. Effective treatment that shows the symptoms to be an illness rather than a religious curse is the best antidote to stigma, he says.