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20 February 2012 | EN
The Firefly device is small enough to fit on a desk
Design that Matters
Two devices to treat jaundice in newborn babies in the developing world will be rolled out later this year.
Jaundice affects about 60 per cent of newborns globally. It is caused by the build-up in the bloodstream of bilirubin — the yellow-coloured remains of old red blood cells — which the newborn's liver cannot break down. In severe cases, bilirubin can enter the brain, causing deafness and brain damage.
Shining blue light onto the baby for 2–3 days breaks down the bilirubin into a form that can be excreted. But this treatment is expensive and is rarely available in rural areas.
The two new machines use high-powered light-emitting diode (LED) lights, which are more energy-efficient and last longer than the compact fluorescent lights usually used.
The first device, Firefly, completed clinical trials in Vietnam in December. All 17 infants treated were cured.
Firefly, invented and developed by US non-profit organisation Design that Matters (DtM), is small enough to sit on a desk.
It is shielded against dust and insects, and a cooling system prevents it overheating in hot climates.
Elizabeth Johansen, director of project development at DtM, told SciDev.Net the device can be used "anywhere in the world". She expects the first batch from a Vietnamese manufacturer later this year.
The second technology, Brilliance, will be the cheapest phototherapy device to be approved by the American Academy of Pediatrics, according to its developer D-Rev, a non-profit technology incubator based in the United States.
Krista Donaldson, chief executive of D-Rev, said that Brilliance will sell for about US$400, compared with US$3,000 for comparable devices.
The technology has been licensed to India's largest manufacturer of neonatal devices and will reach clinics later this year.
Brilliance — which uses passive cooling instead of fans, which can break — has passed bench-top tests and treated two infants.
But because it is based on devices already used in India — apart from the cooling method — it does not require clinical trials, Donaldson said.
William Finseth ( MarketPower International | Canada )
27 February 2012
As a child and as an adult I have suffered several prolonged bouts of jaundice caused by Gilbert's Disease, which is a genetic disorder that causes the body to produce two or four times the normal levels of bilirubin. This occurs most often at times when I have a severe case of diarrhea and vomiting caused by a bacterial infection. This has happened several times while working in Africa. It would be my hope that these devices, such as Brilliance, could be adapted for the adult patient ... possibly using three neo-natal units in series over the length of the adult body.
William Finseth, President
MarketPower International
Ottawa, Canada
mktpower@storm.ca
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29 May 2012