New approaches are needed to reverse the trend of disappointing vaccines against HIV/AIDS, tuberculosis and malaria, argues biotech expert Thomas Egwang.

Neighbouring countries need incentives to coordinate disease control, say health policy experts Ramanan Laxminarayan and colleagues.

Emerging resistance to artemisinin means efforts to track genetic markers and regulate the drug's use must step up, says Priya Shetty.

India urgently needs a permanent dengue surveillance system, say N. Sivagnaname and colleagues.

There is a pressing need for Africa to bolster its pharmaceuticals industry, and that requires the right policy framework, argues Priya Shetty.

Improving health for the poor depends on nurturing local innovations — and learning how to deliver them, argue Abdallah Daar and Peter Singer.

Africa needs to up its game in malaria research, but by doing what it does best, not by replicating Western research, says Linda Nordling.

The revised malaria death toll suggests a need for research into uncertainties in controlling neglected tropical diseases, says Mark Booth.

India's carefully targeted strategy against polio holds lessons for other countries, and for other diseases, argues Priya Shetty.

The Greater Mekong Subregion must build on current initiatives for a lasting response to fake and substandard drugs, says Charles Delacollette.

Eliminating drug-resistant malaria in western Cambodia is key to preventing another malaria disaster, says Nicholas J. White.

Malaria researchers must join forces to present a clear and detailed call for the resources they need, say Ian Boulton and Steve Ward.

Priya Shetty discusses why biomedical research is vital in steering progress towards the Millennium Development Goals.

GM mosquitoes could help control malaria in Africa but their development must involve local scientists, write Paul Eggleston and Mamadou Coulibaly.

Eliminating malaria from Haiti and the Dominican Republic would set a global precedent, say Joseph Keating, Donald Krogstad and Thomas Eisele.

A Nature editorial praises GlaxoSmithKline for sharing its database of potential malaria drugs and urges others to follow suit.

Researchers and donors are not giving nutrition the attention it deserves, says Priya Shetty.

Climate and health experts must collaborate to fight climate-sensitive disease. Ethiopia is leading the way, says Hiwot Teka.

Developing countries must invest in their own research to tackle insect-borne disease and climate change, writes George Kasali.