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NIH Roadmap's Nanomedicine Initiative

In 2005 the US National Institutes of Health (NIH) set up a network of eight Nanomedicine Development Centers to form the NIH Nanomedicine Roadmap Initiative. The collaborative centres are staffed by multidisciplinary research teams including biologists, physicians, mathematicians, engineers and computer scientists. The recently completed first phase of the NIH programme was designed to investigate the chemical and physical properties of nanoscale biological structures. The next phase will be to use this understanding to treat disease.

Population Council: HIV/AIDS

The Population Council is an international non-profit organisation dedicated to supporting biomedical, social sciences and public health research. Its work on HIV/AIDS includes research into the development of an effective microbicide. Its site includes news, information and resources on a wide range of issues relating to HIV/AIDS.

Reservoirs of Antibiotic Resistance

A key APUA research initiative, this project is trying understand the role of commensal bacteria (normal or harmless bacteria) in the spread of antimicrobial resistance.

It is compiling existing commensal isolate data and literature into a web-based bioinformatics tool. It also uses statistical, risk analysis, and mathematical modelling techniques to analyse the data to determine whether the frequency of antibiotic resistance genes in commensals can predict the subsequent emergence of antibiotic resistance in pathogenic bacterial populations. The project has the capacity to award research sub-grants to fund research to produce the data it needs and has awarded 10 research sub-grants since 1997.

ROAR’s fully searchable database is open-access to other researchers in this field, and they can use it to analyse or to input data.

Results for Development Institute

This organisation provides policy analysis, critical information, decision-making tools, and policy advice to governments, civil society organisations and international funders, aiming to stimulate social and economic progress in low- and middle-income countries. It focuses on long-term projects, combining programme implementation with research and analysis. Its website gives an overview of focus areas and current projects in health, good governance, transparency and education. Links to publications are provided, as well as latest news and events.

South Africa Medical Research Council

The South Africa MRC conducts research within the framework of the following six programmes: environment and health, health systems and policy, infection and immunity, molecules to disease, non-communicable diseases, and women and child health. Click here for information on funding opportunities. The website also hosts a section on ethics and human rights, featuring the Council's current guidelines.

South African AIDS Vaccine Initiative

A lead programme of the South Africa, Medical Research Council, SAAVI is committed to the research, development and testing of HIV/AIDS vaccines, working with national and international partners. Its website contains full descriptions of the scientific, clinical and ethical approaches being taken for the development of HIV vaccines tailored to local strains of HIV, including contact details of the researchers involved, funding and updates on progress.

South African National Bioinformatics Institute

SANBI's role is to bring genome information, computational biology, and analytical tools to the South African research community, and to conduct genomic analysis relevant to South African health research and biotechnology. It aims to raise awareness of genome biology, develop analysis systems relevant to South Africa (for example, by providing web-based database tools), develop human resources in bioinformatics (particularly graduate students), and to conduct topical research.

South African National Research Foundation: Indigenous Knowledge

Indigenous Knowledge Systems is a special focus of the National Research Foundation (NRF) in South Africa. The NRF aims to: develop theoretical and methodological paradigms within which to understand the specific characteristics of IK; shed light on the role of IK in nation-building; develop research capacity in the field of IK in South Africa.

Thailand's National Nanotechnology Centre (NANOTEC)

The centre heavily invests in nanotechnology research for health. It has a laboratory dedicated to devising new methods of drug delivery, and another to identifying new molecular targets at which to aim drugs for cancer or other serious diseases. The centre actively seeks to engage in technology transfer with other developing nations.

The Contraceptive Research and Development Program

The Contraceptive Research and Development Program of Eastern Virginia Medical School is dedicated to producing better and safer contraceptives for developing countries, to protect against the transmission of HIV and other sexually transmitted infections. Its projects include the Bill and Melinda Gates-funded Global Microbicide Project, which funds pilot and major research projects, and the Consortium for Industrial Collaboration in Contraceptive Research (CICCR). The website contains limited information about its activities, and guidelines on how to apply for funds.

The Institute for Genomic Research

Founded in 1992, The Institute for Genomic Research (TIGR) is a not-for-profit research institute whose primary research interests are in structural, functional and comparative analysis of genomes and gene products from a wide variety of organisms. TIGR has completed the genome sequence of many pathogens including those that cause cholera, tuberculosis and meningitis. It also contributed to the international human genome sequencing project. TIGR is involved in numerous collaborations with academic institutions around the world including several with scientists in developing countries.

The Institute of Human Virology

The Institute of Human Virology, in Maryland, United States, is a multidisciplinary research institute dedicated to finding new treatments and vaccines for HIV, hepatitis C, and other diseases. Its main focus is basic and clinical HIV/AIDS research, including vaccine development. The website is well organised with information and links to collaborators around the world, as well as a list of clinical trials.

The Intermittent Preventive Treatment in Infants (IPTi) Consortium

The IPTi Consortium consists of leading centres of malaria research in Africa, Europe and the United States, and two UN agencies — the World Health Organization and UNICEF. It has developed a comprehensive research and implementation agenda to quickly resolve scientific questions on whether intermittent preventative treatment with malaria drugs is safe and effective for infants. By answering these questions, it aims to move the intervention into policy and practice.

The International Agency for Research on Cancer

IARC's mission is to undertake research on the causes of human cancer, the mechanisms of carcinogenesis, and to develop scientific strategies for cancer control. It develops strategies at a theoretical level, however, and does not get involved in direct implementation nor contribute to the formulation of policies or legislation. The agency also does not on the whole contribute to research in to cancer treatments.

The agency publishes several key publications on epidemiology (especially of the disease in developing countries), pathology and genetics. To encourage research, the agency offers several fellowships, scholarships and training courses.

The International Network on Household Water Treatment and Safe Storage

This informal network, part of the University of Carolina's Gillings School of Global Public Health, brings together over 100 organisations working to promote and scale up adoption of practices and technologies that improve drinking water quality for vulnerable populations.

By providing information and promoting independent research, the network aims to reduce water-related diseases by promoting water treatment and safe water storage at the household level. The website provides an overview of the network, working groups and guiding principles. It lists participating organisations and relevant events, and publishes a monthly newsletter.

The National Center for Minority Health and Health Disparities (NCMHD) Center of Excellence for Nutritional Genomics

The NCMHD Center of Excellence for Nutritional Genomics — a collaboration between five university departments, research institutes and hospitals — publishes news, information and commentary on research that cuts across nutrition, genomics, and health. It also provides a list of definitions, image library and links to relevant sites and users can sign-up to receive email alerts of the latest news in nutrigenomics.

The centre's research focuses on genomics, proteomics and bioinformatics to identify genes that might affect health risks from a poor diet. Its goal is to devise genome-based nutritional interventions to prevent or treat diseases such as asthma, obesity, and diabetes.

US National Human Genome Research Institute

The National Human Genome Research Institute led the US contribution to the sequencing of the human genome. Following the completion of the Human Genome Project, NHGRI has moved into areas of genetic and genomic research aimed at improving human health and fighting disease. It also supports the investigation of ethical, legal and social implications surrounding genetics research, and conducts educational outreach activities in genetics and genomics.

US National Institutes of Allergies and Infectious Diseases: Division of AIDS

This division of the US National Institutes of Health conducts basic research into HIV biology, vaccines and new therapies. The site includes fact sheets, brochures, a glossary of HIV/AIDS terms and links to other resources.

Wellcome Trust Sanger Institute

The Wellcome Trust Sanger Institute was set up in 1992 by the Wellcome Trust and the UK Medical Research Council in order to further our knowledge of genomes. It is one of the world's leading genomics centres, and is responsible for the completion of the sequence of approximately one-third of the human genome as well as genomes of model organisms such as mouse and zebrafish, and more than 90 pathogen genomes. It is engaged in a range of post-genomic programmes designed to understand the biological function of genes and their relevance to our health.
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