Science and Development Network
News, views and information about science, technology and the developing world
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Definitions
- Antibiotic resistance
- Bird flu
- Climate change & insect-borne disease
- Genomics
- Malaria
- Nanotechnology for health
- Tuberculosis
List of terms for Genomics
M
Marker
A specific feature at an identified physical location on a chromosome, whose inheritance can be followed. The position of a gene implicated in a particular phenotypic effect can be defined through its linkage to such markers. [WHO: Genomics and World Health]
Microarray
A grid of nucleic acid molecules of known composition linked to a solid substrate, which can be probed to reveal changes in gene expression relative to a control sample. Microarray technology, which is also known as “DNA chip” technology, allows the expression of many thousands of genes to be assessed in a single experiment. [WHO: Genomics and World Health]
Multifactorial (multigenic) disease
A disease whose pathology is dependent on the complex interplay of several genetic and environmental factors. [WHO: Genomics and World Health]
Mutation
A structural change in a DNA sequence resulting from uncorrected errors during DNA replication. [WHO: Genomics and World Health]
