This report outlines the role that science, technology and innovation can play in implementing the Millennium Development Goals (MDGs). It draws from lessons learned over the past five decades, and describes actions needed to help achieve the MDGs through technological innovation, including building scientific infrastructure, investing in education and promoting business activities in science and technology.

The report acknowledges three main actors in technological innovation: governments, academic institutions and private enterprise. It argues that they must work together to improve the policy environment, technological infrastructure and capacity-building in developing nations. It suggests that global partnerships, advising policymakers and good governance should be encouraged, and points out that the diversity of political environments and resources means that countries should not have a one-size-fits-all approach to policy development.

This policy guide, published by the UN Food and Agriculture Organization, lays out the key requirements for developing effective and efficient smallholder seed enterprises, and how the process can be supported through policy. It argues that the best way to ensure production and distribution of quality seed in developing countries may be to support smallholder seed enterprises, but this approach can only succeed if the right policies and capacities are in place.

The report gives an overview of each stage of the evolution of the seed sector and possible interventions, as well as priority activities for policy support at each stage. These may include national policies to encourage linkages between research, quality control and financial systems that can support local smallholders in taking over seed production from the public sector. It outlines specific requirements for the establishment and sustainable operation of smallholder seed enterprises.

In 2003, the Gates foundation infused new vigour into global health efforts by declaring that the 21st century's "grand challenges" included developing new vaccines and overcoming drug resistance. This new grand challenges initiative, launched by a collaboration of top global chronic disease experts, identifies priorities in tackling diseases like diabetes and cardiovascular disease, and explains in detail how research should be directed to meet each challenge (a challenge was defined as a critical barrier that if removed would help solve an important health problem).

To distill the range of opinions and priorities, the coordinators sought input from 155 stakeholders from different countries and disciplines. The initiative requires the participation of agencies like the WHO, individual governments, and non-governmental organisations as well as civil society and business if it is to succeed. The authors point out that the Gates initiative was linked to large funding, whereas this project will rely on multiple funding agencies to coordinate on these priorities.