This report outlines the first coherent strategy drawn up by the UN to address dryland management, taking into account environmental concerns and the well-being of dryland communities. It examines the relationship between drylands and climate change, food security and livelihoods, and highlights ways in which the UN is working to mainstream drylands into policymaking processes.

Climate change is already having an impact on crop yields and nutrition in areas that rely on rain-fed agriculture, according to the report, and these impacts will intensify by 2020 in parts of Sub-Saharan Africa, Asia and Latin America. The impacts of climate change may be most pronounced in Sub-Saharan Africa and South Asia, suggesting that those already vulnerable will be affected the most.

A key message is that the international community has an opportunity to address the underlying causes of dryland degradation. The report concludes that global cooperation must be intensified if the ten-year strategic plan of the UN Convention to Combat Desertification — whose aim is to tackle desertification and degradation — and the Millennium Development Goals are to be achieved.

This report, from the Australian Centre for International Agricultural Research (ACIAR), highlights the results of research into what drives and inhibits the uptake of new crop-livestock farming techniques by small-scale cattle farms in Asian countries. The authors describe five farming systems in China, Indonesia and Vietnam that have attempted to increase beef production and profitability by integrating new farming knowledge and technology with help from ACIAR. Using these case studies, the authors draw out lessons learned for future initiatives. Key findings include the importance of partnering with local people who have a good understanding of the farming system, and having a realistic expectation of the scale of improvements that can be made with new technologies.

This report explores the role of agricultural growth in reducing and preventing undernutrition — deficiencies in energy, protein, and essential vitamins and minerals.

It describes how agricultural growth increases the capacity of households to produce more nutritious food and to buy more nutritious food by boosting income levels. Agricultural growth also improves nutrition through a broader effect on the economy, such as increasing government revenues to fund education, health, infrastructure, and nutrition intervention programmes.

The report gives an overview of the relationship between nutrition and growth, examines different growth patterns and their nutritional outcomes, and identifies factors that influence this dynamic — such as a country's stage of economic development.

A new paradigm for agricultural development is needed, says the report, where agricultural growth leads not only to increased production and reduced poverty, but also to improved nutrition. It concludes with recommendations for future research, and aims to provide policymakers with knowledge about development and investment strategies that can improve nutritional outcomes.

This report provides an overview of fisheries and aquaculture, future challenges and the technological tools available to help manage them. It reveals the key role of this sector in meeting global fish demand, as well as its importance as a source of cash and high-quality protein — particularly in poorer countries.

A section devoted to case-studies reviews current scientific knowledge of the impacts of a changing climate. It also highlights a range of issues including standards and certification, development of aquaculture in South-East Asia and the use of geographical information systems to manage aquaculture.

Elsewhere, the document outlines efforts to control illegal, unreported and unregulated fishing by establishing trade measures and improving the collection of global records about fishing vessels.

The report also pinpoints challenges ahead, including biodiversity protection and a greater demand to address concerns about public health and environmental protection.

The Center is a US-based think tank that aims to help decision-makers innovatively address global health issues through multidisciplinary research. Key projects include developing policy proposals to deal with antibiotic resistance in low- and middle-income countries, and a financing mechanism to increase access to affordable malaria therapies. The website features a blog, lists details of projects, and includes links to relevant presentations and publications.

This report presents evidence that people with mental health conditions meet major criteria for vulnerability and should be targeted for protection by development programmes. Mental illness such as schizophrenia, depression or bipolar disorder are common but largely neglected.

The WHO makes the case that because of their vulnerability, people with mental health problems need to be given opportunities for education and work, and to be included in decisions that affect them.

It argues that mental health should be built into sectoral and broader plans for development, with government agencies, NGOs and other stakeholders playing a key role in ensuring this. To make implementation a reality, interventions and mainstreaming efforts should be funded adequately, and recipients of development aid should be encouraged to address the needs of people with mental health conditions. The report recommends actions as a starting point towards these aims.

This handbook offers developing countries guidance on how to conduct technology needs assessments systematically to address climate change.

It was prepared by the UN Development Programme (UNDP), in collaboration with the Expert Group on Technology Transfer of the UN Framework Convention on Climate Change (UNFCCC) Secretariat and the Climate Technology Initiative.

This updated version of the 2004 handbook provides a more detailed framework for the development and implementation of needs assessments designed to help countries make informed choices on the technologies they can adopt to mitigate and adapt to the impacts of climate change. In particular, it advises on how to identify, assess and prioritise technologies. It also examines ways to support capacity building and help establish environments to enable technology transfer.

This opinion article argues that excessive concern about the risks of nanotechnology in developing countries could derail its progress and hinder the enormous health, environment and economic benefits to be gained from nanotechnology research. The authors identify the developing countries making the most advances in nanotechnology, those in the middle ground, and the "up and comers".

This report from PLoS Medicine argues that nanotechnology has a role in the development of low-income countries. The authors survey 85 experts worldwide and rank the top ten nanotech applications most likely to benefit developing nations. They outline how these applications can help meet the Millennium Development Goals. The paper calls for an initiative to identify "grand challenges" in nanotechnology for global health, which since the publication of this paper are now underway.

This report, published by the Meridian Institute describes the growing interest of developing countries including Brazil, China, India and South Africa, in nanotechnology. The ways nanotechnology applications could solve health, sanitation, and pollution problems and provide faster, cheaper information and communication technology are outlined. The challenges of using and developing nanotechnology for and in developing nations including the roles and responsibilities of different stakeholders are also discussed.

The Meridian Institute says nanotechnology can play a role in achieving the UN Millennium Development Goals. As a result, rich nations should dedicate a reasonable portion of their overseas development assistance to nanotechnology.

Mohamed Hassan at the Academy of Sciences for the Developing World (TWAS) argues that the nanotechnology boom will not lead to a divide between developed and developing countries due to the transformation of 21st century global science. Hassan says Brazil, China and India are swiftly developing nanotech capabilities. Instead, he warns of a South-South divide as poorer nations struggle to catch up. To avoid this, Hassan recommends that developing nations create networks between universities and research centres to share nanotech expertise.

This review article outlines the basic principles of traditional Chinese and Indian medicine, and the differences in how these are being integrated into national health systems. The authors discuss progress in drug discovery including traditional medicinal plants and the role of supporting industries — from breeders to manufacturers — in commercialising traditional medicine.

This report from the Chinese branch of the UN Development Programme investigates how China can reduce its heavy dependence on energy and resource consumption and move to a low-carbon economy. The authors suggest that the key lies in strengthening institutions, integrating policies, and enforcing implementation.

This series of commentaries and research articles — published by The Lancet, the Peking University Health Sciences Centre and the China Medical Board — addresses China's major health challenges, strategies and future. It has been produced by a group of 63 scientists from 10 countries with Chinese scientists making up two-thirds of the authors.

The research papers give scientific evidence on key health issues including the emergence and control of both infectious and chronic non-infectious diseases in China as well as the performance of China's healthcare system.

Authors of the series' commentaries further discuss a range of topical issues affecting China's health system, including the state of biomedical science and technology (see 'Progress in Chinese biomedicine a massive challenge'), medical research ethics, the lessons learnt from China's schistosomiasis control programme and the challenges the country faces in controlling HIV/AIDS.

Cardiovascular disease accounts for 30% of deaths worldwide and 10% of all years of healthy life lost to disease, and the figures are nearly as high in developing countries — 27 per cent and 9 per cent respectively. This compares with 10% of lives lost worldwide from HIV/AIDS, TB and malaria put together (12% in developing countries). So why have donors not invested as heavily into tackling non-communicable chronic diseases as they have with infectious ones? The authors of this article suggest several reasons: infectious diseases are in some ways easier to solve by a vaccine or drugs so it might seem sensible to use precious funding this way; Western donors may want to see epidemics contained quickly to avoid global spread; pictures of small African children dying of AIDS are more heartrending than a middle-aged man with hypertension, even if that man is supporting a large family; there is a myth that chronic diseases are more costly to prevent than infectious ones. This last issue is one that should be tackled strongly to spread awareness that low-cost methods can have an enormous effect on chronic diseases.

Vaccination for infectious diseases is a vital method of prophylaxis, and has transformed modern medicine. By contrast, research into vaccines against chronic diseases has been less successful, in part because of the increased complexity involved.

In this opinion piece, the authors outline the prospects for the development of chronic disease vaccines. These might not need to rely on the traditional method of inducing the body to produce antibodies, but rather on introducing monoclonal antibodies against specific proteins — this has so far worked well against Crohn's disease and rheumatoid arthritis.

The authors outline key hurdles in developing a successful therapeutic vaccine. Safety and efficacy are two obvious ones, but there is a third that is unique to vaccines for chronic diseases. Because these vaccines would block bodily chemicals — such as cytokines or hormones — it would not be acceptable for a vaccine to induce a life-long block (unlike a malaria vaccine, for example, where a lifelong block would be ideal).

These might be particularly useful in developing countries, say the authors. Because prophylaxis with vaccines is already a familiar concept, there should be no problem with patients' compliance, and judicious partnerships between public and private organisations could mean the vaccines are produced cheaply.

The Millennium Development Goals (MDGs) practically define health efforts in the 21st century, but they virtually ignore non-communicable diseases such as mental health, say these authors. This is despite evidence that mental health disorders are among the most important cause of sickness and disability and even premature mortality. The authors argue that tackling mental health problems will be vital to achieving the MDGs, and three in particular — eradicating poverty, reducing child mortality, and improving maternal health.

Poverty and hunger are well-recognised risk factors for mental health, but mental health also makes it harder for people to escape the hunger trap. Mothers who are depressed during pregnancy and post natally, are more likely to have underweight babies; not only that, the illness means these mothers are more likely to stop breastfeeding and less likely to ensure their children are properly immunised than mothers without depression.

The authors advocate that strengthening basic health-care systems should be holistic. For example, developing countries need more and better-trained health workers but they should not only know how to deliver babies but also how to counsel new mothers. HIV/AIDS programmes, as another example, should ensure that individuals not only have good access to antiretrovirals but also to treatment for depression if they need it.

Schizophrenia is relatively rare — affecting 1% of the world's population — but is arguably one of the most severe mental illnesses. Diagnosing and treating it can be hard enough in developed countries; the challenges are magnified in developing nations with inadequate health systems; few trained staff; and pervasive social stigma. So how best to treat it? In this debate, three psychiatrists offer their different viewpoints.

Vikram Patel, at the London School of Hygiene and Tropical Medicine, says the shortage of mental health specialists means that the most effective way of spreading the expertise around might be for non-specialist health workers or community representatives to be trained to bear the brunt of providing first-line mental health services. Saeed Farooq, at Pakistan's Lady Reading Hospital, argues that the principles of the WHO's DOTS TB programme, in which patients are given an uninterrupted supply of medication taken under close supervision, could be used to treat schizophrenia. The rationale is that missing medication for schizophrenia, which can be common given the cognitive impairment associated with the illness, has serious consequences and can lead to much higher risks of relapse. R. Thara, director of the Schizophrenia Research Foundation, Chennai, India, advocates tackling stigma by offering proper treatment. In India at least, he says, the mystification of mental illness is intensified by a lack of awareness about schizophrenia and also by "magico-religious" beliefs. Effective treatment that shows the symptoms to be an illness rather than a religious curse is the best antidote to stigma, he says.